Monday, September 29, 2014
Medicinal Mushroom Cordyceps Reduces Liver Cancer Growth
AUTHOR BRIDGET GREENWOOD
The medicinal mushroom Cordyceps cicadae was tested for its anti-cancer properties. Would Cordyceps cicadae be effective in treating liver cancer? Results are promising.
Liver cancer is one of the world’s most diagnosed cancers. There are several types of liver cancer, and Hepatocellular carcinoma is the most common. Incidences of liver cancer are particularly high in East Asia. In China, for example, liver cancer has the second highest mortality rates for men.
This high incidence of liver cancer in China is thought to result from the widespread consumption of grains contaminated with aflatoxins, though liver virus infections like Hepatitis B and C are also factors. Aflatoxins are one of the most carcinogenic substances in existence.
Liver cancer is treated with surgery—transplant is often a last resort. Radiation therapy and chemotherapy are also usual treatments, though the harsh side effects mean improved techniques are continually being developed.
Researchers (Hualin Wang, Jing Zhang, et al) from the University of Hong Kong, developed an in vitro experiment to investigate treating Hepatocellular carcinoma with extracts from the medicinal mushroom Cordyceps.
Medicinal mushrooms like Cordyceps are often used in conjunction with chemotherapy drugs, as the mushrooms may boost the immune system and decrease the side effects. Cordyceps Sinensis has been shown to possess anticancer properties. Would Cordyceps cicadae be effective against liver cancer cells?
Cordyceps treats liver cancer: experiment
University of Hong Kong 300x200 Medicinal Mushroom Cordyceps Reduces Liver Cancer Growth
Cordyceps medicinal mushroom may help with liver cancer: University of Hong Kong study
The researchers treated human liver cancer cells with water extracts of Cordyceps for a 48 hour period. The cancer cells were then harvested and analyzed using mass spectrometry and other methods.
Cordyceps was shown to inhibit cancer cell growth in a dose-dependent manner. This reduction of cancer cell proliferation was significant as the Cordyceps targeted specific proteins in the cancer cells’ growth mechanism.
The researchers concluded that water extract of Cordyceps cicadae reduced the human liver cancer cell growth via cell cycle arrest.
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