Saturday, October 25, 2014
Colon Cancer and Reishi
Colon Cancer and Reishi
AUTHOR CELIA LEUNG
reishi medicinal mushroom and colon cancer
Colon cancer, also known as colorectal or bowel cancer is a cancer that originates from uncontrolled cell growth in the colon, rectum or appendix. It is believed to be the fourth most common cause of cancer death, with over a million individuals being diagnosed annually worldwide. Symptoms usually include rectal bleeding, decrease in number of red blood cells, weight loss and changes in bowel movement. Treatment options for colon cancer can include a combination of surgery, chemotherapy, radiation or radiofrequency ablation. But in a recent study conducted by Hunan Agricultural University in China, researchers set out to examine the treatment potential of Reishi medicinal mushroom for colon cancer cells.
Reishi, also known as Lingzhi mushroom and Ganoderma Lucidum, is one of the oldest medicinal mushrooms since it has been used in Traditional Chinese Medicine (TCM) for over 2,000 years. It is believed that reishi medicinal mushrooms have antitumor and anti-cancer properties. Previous research suggests they also help enhance immune system functioning, reduce feelings of depression, lowers blood pressure, and treats hepatitis, bronchitis and bronchial asthma.
The Effects of Reishi Polysaccharides on Colon Cancer Cells
For the experiment researchers Zengenni Liang, Yu-Tong Guo, You-Jin Yi, Ren-Cai Wang, Qiu-Long Hu and Xing-Yao Xiong isolated extracts from Reishi medicinal mushroom called GLP (Ganoderma lucidumpolysaccharides). They tested the reishi extracts on human colon cancer cells and measured its anticancer effects using various assays and observations on wound-healing. A control group of untreated cells were also used as a comparison. Cell apoptosis (programmed cell death) induced by Reishi was also observed on the colon cancer cells.
After analyzing the data, the researchers found that reishi extracts exhibited a dose and time-dependent inhibitory effect on the proliferation of human colon cancer cells in their experiment. In particular, they observed that Ganoderma lucidumpolysaccharides helped suppress cell growth and migration of human colon cancer cells. Another observation the researchers made was that reishi polysaccharides induced apoptosis by promoting the release of lactate dehydrogenase and increased intracellular calcium levels. Based on these results, the researchers believe that reishi extracts can be a beneficial, nontoxic form of treatment for colon cancer.
Please check with your doctor before taking any mushroom supplements. Do not discontinue or make changes to your medication without consulting with your physician first! The author of this story is a staff writer for National Nutraceuticals’ online news portals, such as Amino Acid Information Center athttp://www.aminoacidinformation.com.
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